Sermorelin Calculator
A vial strength and a water volume give a concentration. A concentration and a syringe give units. Worked for the research-grade vial sizes tracked across vendors.
Last reviewed: September 27, 2026
Vial strength and water volume give a concentration; a dose then gives the unit mark it corresponds to.
For research purposes only. Always verify calculations independently before use.
On this page
What reconstitution is
Research-grade sermorelin, like other research peptides, ships from vendors as a lyophilized (freeze-dried) powder sealed in a vial. Reconstitution is the act of dissolving that powder in a liquid — typically bacteriostatic water — which turns a fixed mass of peptide (the vial’s labeled mg content) into a solution with a defined concentration, measurable in volume with a syringe. The mass doesn’t change; only how that mass is distributed through a volume of liquid changes.
Sermorelin’s FDA-approved product, Geref, was discontinued in 2008 — not for safety or efficacy reasons — and there is no current sermorelin label in force. This page works the generic arithmetic (concentration = mass ÷ volume) for the research-grade vial sizes vendors sell today. For the compound’s mechanism, trial evidence, and FDA history, see the sermorelin profile.
What sizes does research-grade sermorelin come in?
Two sizes, 5 mg and 10 mg, are each carried by three or more of the vendors tracked here — the sizes with a real, multi-vendor market rather than one vendor’s own catalog choice. They are listed below with the number of vendors carrying each, read from live price data rather than a list kept by hand, which is why the calculator above offers exactly these as one-tap sizes.
| Vial size | Vendors tracking this size |
|---|---|
| 5 mg | 17 |
| 10 mg | 26 |
The arithmetic, worked
Concentration (mg/mL) equals the vial’s total mg divided by the water volume in mL. Micrograms per syringe unit, on a U-100 syringe (100 units = 1 mL), equals that concentration multiplied by 10. The table below reports both figures at two illustrative water volumes for each tracked size — as a statement of what each volume does to the concentration, not a recommendation of either:
| Vial size | At 1 mL water | At 2 mL water |
|---|---|---|
| 5 mg | 5 mg/mL — 50 mcg/unit | 2.5 mg/mL — 25 mcg/unit |
| 10 mg | 10 mg/mL — 100 mcg/unit | 5 mg/mL — 50 mcg/unit |
Doubling the water volume halves the concentration and halves the mcg delivered per unit drawn — the relationship is linear in both directions. The general dosage calculator runs this same arithmetic for any vial size and water volume, including ones outside the table above.
Units to draw, by vial size and dose
Every cell is the U-100 unit mark a given dose comes to, for a given vial strength, at 2 mL of bacteriostatic water. The rows are the research-grade vial sizes three or more tracked vendors carry; the columns are round microgram values spanning the sermorelin profile’s own table and the cited human-trial range, reported flat and not as a schedule. See the sermorelin profile for the mechanism, trial evidence, and the dosing literature.
| Vial | 100 mcg | 250 mcg | 500 mcg | 1000 mcg | 2000 mcg |
|---|---|---|---|---|---|
| 5 mg | 4.0 | 10.0 | 20.0 | 40.0 | 80.0 |
| 10 mg | 2.0 | 5.0 | 10.0 | 20.0 | 40.0 |
Figures over 100 are shown in amber: they exceed a 1 mL U-100 barrel at this water volume, so that combination does not fit one syringe. More water lowers the concentration and raises the unit count; less water does the reverse. The calculator above works any vial, volume and dose, in either direction.
What one vial comes to
Both tracked sizes, worked at 2 mL. “Doses per vial” is the vial’s total divided by the dose — how many times that amount is present in the vial, before any loss in handling.
10 mg vial at 2 mL — 5.00 mg/mL
| Dose | Units to draw | Draw volume | Doses per vial |
|---|---|---|---|
| 100 mcg | 2.0 | 0.02 mL | 100.0 |
| 250 mcg | 5.0 | 0.05 mL | 40.0 |
| 500 mcg | 10.0 | 0.10 mL | 20.0 |
| 1000 mcg | 20.0 | 0.20 mL | 10.0 |
| 2000 mcg | 40.0 | 0.40 mL | 5.0 |
5 mg vial at 2 mL — 2.50 mg/mL
| Dose | Units to draw | Draw volume | Doses per vial |
|---|---|---|---|
| 100 mcg | 4.0 | 0.04 mL | 50.0 |
| 250 mcg | 10.0 | 0.10 mL | 20.0 |
| 500 mcg | 20.0 | 0.20 mL | 10.0 |
| 1000 mcg | 40.0 | 0.40 mL | 5.0 |
| 2000 mcg | 80.0 | 0.80 mL | 2.5 |
What changes the answer
- Water volume. Concentration is inversely proportional to water volume — the table above shows this directly. A larger water volume produces a lower concentration, meaning more units are needed to reach the same mcg amount, which can exceed a syringe’s barrel capacity at low concentrations and high mcg amounts.
- Vial size. For a fixed water volume, concentration is directly proportional to vial size — a 10 mg vial reconstituted with 1 mL is twice the concentration of a 5 mg vial reconstituted the same way.
- Syringe calibration. Every figure above assumes a U-100 syringe (100 units = 1 mL), the standard for peptide research (see the syringes and injection guide). A different calibration — U-40, for instance — would report a different units figure for the identical physical volume; it does not change the concentration or the mcg delivered.
How long does reconstituted sermorelin last?
Sermorelin’s FDA-approved product, Geref, was discontinued in 2008 — not for safety or efficacy reasons, per the sermorelin profile — so there is no current manufacturer label to cite for reconstituted-solution stability.
Reconstituted solution: 2–8°C, refrigerated, is standard practice once dissolved. Prof. Peptide has not identified a manufacturer label, published study, or lab document establishing how long reconstituted research-grade sermorelin remains stable — this page does not state a duration as fact.
FAQ
What is reconstitution?
Does the water volume change how much peptide is in the vial?
What syringe do the unit figures on this page assume?
Why doesn't this page say how much water to add or what dose to draw?
Is this the same as Geref's own reconstitution?
What if my vial's size isn't in the table below?
How much BAC water for a 5mg sermorelin vial?
How much BAC water for a 10mg sermorelin vial?
References
- Sermorelin’s FDA approval history and cited human-trial dosing, as already sourced and verified on the sermorelin profile. See that page’s own references section for the underlying studies.
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