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MOTS-c Calculator

A vial strength and a water volume give a concentration. A concentration and a syringe give units. Worked for the vial sizes tracked across vendors — not generic examples.

Last reviewed: September 21, 2026

Vial strength and water volume give a concentration; a dose then gives the unit mark it corresponds to.

MOTS-c

Vial sizes vendors carry — tap to fill:

How much bac water?
Syringe barrel

For research purposes only. Always verify calculations independently before use.

On this page
  1. 1.What reconstitution is
  2. 2.What sizes does MOTS-c come in?
  3. 3.The arithmetic, worked
  4. 4.Units to draw, by vial size and dose
  5. 5.What one vial comes to
  6. 6.What changes the answer
  7. 7.How long does reconstituted MOTS-c last?
  8. 8.FAQ
  9. 9.References

What reconstitution is

MOTS-c, like other research peptides, ships from vendors as a lyophilized (freeze-dried) powder sealed in a vial. Reconstitution is the act of dissolving that powder in a liquid — typically bacteriostatic water — which turns a fixed mass of peptide (the vial’s labeled mg content) into a solution with a defined concentration, measurable in volume with a syringe. The mass doesn’t change; only how that mass is distributed through a volume of liquid changes.

MOTS-c is investigational, not FDA-approved for any indication, so there is no manufacturer instruction for reconstituting it. The math below is generic pharmaceutical arithmetic (concentration = mass ÷ volume), the same relationship that governs any lyophilized compound dissolved in a diluent, applied to the vial sizes MOTS-c is actually sold in. For the compound’s mechanism, evidence base, and regulatory status, see the MOTS-c profile.

What sizes does MOTS-c come in?

Three sizes, from 10 mg to 40 mg, are each carried by three or more of the vendors tracked here — the sizes with a real, multi-vendor market rather than one vendor’s own catalog choice. They are listed below with the number of vendors carrying each, read from live price data rather than a list kept by hand, which is why the calculator above offers exactly these as one-tap sizes.

Vial sizeVendors tracking this size
10 mg42
20 mg7
40 mg20

The arithmetic, worked

Concentration (mg/mL) equals the vial’s total mg divided by the water volume in mL. Micrograms per syringe unit, on a U-100 syringe (100 units = 1 mL), equals that concentration multiplied by 10. The table below reports both figures at two illustrative water volumes for each tracked size — as a statement of what each volume does to the concentration, not a recommendation of either:

Vial sizeAt 1 mL waterAt 2 mL water
10 mg10 mg/mL — 100 mcg/unit5 mg/mL — 50 mcg/unit
20 mg20 mg/mL — 200 mcg/unit10 mg/mL — 100 mcg/unit
40 mg40 mg/mL — 400 mcg/unit20 mg/mL — 200 mcg/unit

Doubling the water volume halves the concentration and halves the mcg delivered per unit drawn — the relationship is linear in both directions. The general dosage calculator runs this same arithmetic for any vial size and water volume, including ones outside the table above.

Units to draw, by vial size and dose

Every cell is the U-100 unit mark a given dose comes to, for a given vial strength, at 2 mL of bacteriostatic water. The rows are the vial sizes three or more tracked vendors carry; the columns are round milligram values spanning the range MOTS-c is commonly discussed at — not a schedule. MOTS-c’s doses run large relative to its smallest tracked vial, so several cells below exceed a single 1 mL syringe barrel at this water volume — that is the arithmetic, not an error. See the MOTS-c profile for the evidence base and what is and isn’t established.

Vial2 mg4 mg5 mg6 mg8 mg10 mg
10 mg40.080.0100.0120.0160.0200.0
20 mg20.040.050.060.080.0100.0
40 mg10.020.025.030.040.050.0

Figures over 100 are shown in amber: they exceed a 1 mL U-100 barrel at this water volume, so that combination does not fit one syringe. More water lowers the concentration and raises the unit count; less water does the reverse. The calculator above works any vial, volume and dose, in either direction.

What one vial comes to

The three tracked sizes, worked at 2 mL. “Doses per vial” is the vial’s total divided by the dose — how many times that amount is present in the vial, before any loss in handling.

10 mg vial at 2 mL — 5.00 mg/mL

DoseUnits to drawDraw volumeDoses per vial
2 mg40.00.40 mL5.0
4 mg80.00.80 mL2.5
5 mg100.01.00 mL2.0
6 mg120.01.20 mL1.7
8 mg160.01.60 mL1.3
10 mg200.02.00 mL1.0

40 mg vial at 2 mL — 20.00 mg/mL

DoseUnits to drawDraw volumeDoses per vial
2 mg10.00.10 mL20.0
4 mg20.00.20 mL10.0
5 mg25.00.25 mL8.0
6 mg30.00.30 mL6.7
8 mg40.00.40 mL5.0
10 mg50.00.50 mL4.0

20 mg vial at 2 mL — 10.00 mg/mL

DoseUnits to drawDraw volumeDoses per vial
2 mg20.00.20 mL10.0
4 mg40.00.40 mL5.0
5 mg50.00.50 mL4.0
6 mg60.00.60 mL3.3
8 mg80.00.80 mL2.5
10 mg100.01.00 mL2.0

What changes the answer

  • Water volume. Concentration is inversely proportional to water volume — the table above shows this directly. A larger water volume produces a lower concentration, meaning more units are needed to reach the same mg amount, which can exceed a syringe’s barrel capacity at low concentrations and high mg amounts.
  • Vial size. For a fixed water volume, concentration is directly proportional to vial size — a 40 mg vial reconstituted with 1 mL is four times the concentration of a 10 mg vial reconstituted the same way.
  • Syringe calibration. Every figure above assumes a U-100 syringe (100 units = 1 mL), the standard for peptide research (see the syringes and injection guide). A different calibration — U-40, for instance — would report a different units figure for the identical physical volume; it does not change the concentration or the mg delivered.

How long does reconstituted MOTS-c last?

MOTS-c is investigational and not FDA-approved for any indication, and has no manufacturer label of any kind — not for the lyophilized powder, and not for a reconstituted solution.

Prof. Peptide has not identified a manufacturer label, published study, or lab document establishing how long reconstituted research-grade MOTS-c remains stable — this page does not state a duration as fact. Refrigeration (2–8°C) once dissolved is standard practice, reported the same way across research peptides generally, not a figure specific to MOTS-c’s own stability.

FAQ

What is reconstitution?
Reconstitution is dissolving a lyophilized (freeze-dried) peptide powder in a liquid — typically bacteriostatic water — to turn it into a solution that can be measured with a syringe. The peptide's total mass doesn't change; dissolving it in liquid just makes it measurable in volume.
Does the water volume change how much peptide is in the vial?
No. A 10 mg vial contains 10 mg of MOTS-c regardless of how much water is added. What changes is the concentration — milligrams per milliliter — and therefore how many syringe units correspond to a given milligram amount.
What syringe do the unit figures on this page assume?
A U-100 insulin syringe, where 100 units equals 1 mL. This is the standard syringe for peptide research — see the syringes and injection guide for barrel sizes and needle gauge.
Why doesn't this page say how much water to add or what dose to draw?
Both of those require choosing a number for the reader — a reconstitution volume and a target dose — and this page reports arithmetic, not a chosen protocol. The tables below show what a given water volume does to a given vial's concentration; how much water to use and what to inject are decisions outside what this page states.
What if my vial's size isn't in the table below?
The table covers sizes carried by 3 or more tracked vendors. A size outside that list can still be worked the same way: concentration (mg/mL) equals the vial's total mg divided by the water volume in mL, and mcg per syringe unit equals that concentration times 10 (on a U-100 syringe). The general dosage calculator performs this for any size.
How much BAC water for a 10mg MOTS-c vial?
A 10 mg vial holds 10 mg of MOTS-c whatever volume of bacteriostatic water is added — the water sets the concentration, not the amount in the vial. At 1 mL that vial reads 10 mg/mL, so one unit on a U-100 syringe carries 100 mcg. At 2 mL it reads 5.00 mg/mL and one unit carries 50 mcg. At 3 mL it reads 3.33 mg/mL and one unit carries 33.3 mcg. Which of those volumes to add is a choice this page does not make; the calculator above works any combination, in either direction.
How much BAC water for a 20mg MOTS-c vial?
A 20 mg vial holds 20 mg of MOTS-c whatever volume of bacteriostatic water is added — the water sets the concentration, not the amount in the vial. At 1 mL that vial reads 20 mg/mL, so one unit on a U-100 syringe carries 200 mcg. At 2 mL it reads 10.00 mg/mL and one unit carries 100 mcg. At 3 mL it reads 6.67 mg/mL and one unit carries 66.7 mcg. Which of those volumes to add is a choice this page does not make; the calculator above works any combination, in either direction.
How much BAC water for a 40mg MOTS-c vial?
A 40 mg vial holds 40 mg of MOTS-c whatever volume of bacteriostatic water is added — the water sets the concentration, not the amount in the vial. At 1 mL that vial reads 40 mg/mL, so one unit on a U-100 syringe carries 400 mcg. At 2 mL it reads 20.00 mg/mL and one unit carries 200 mcg. At 3 mL it reads 13.33 mg/mL and one unit carries 133.3 mcg. Which of those volumes to add is a choice this page does not make; the calculator above works any combination, in either direction.

References

  1. See the MOTS-c profile for the compound’s evidence base and regulatory status. This page reports arithmetic only and cites no additional source of its own beyond the generic reconstitution relationship (concentration = mass ÷ volume).

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