Metabolic & GLP-1 Peptides

Metabolic and GLP-1 peptides regulate appetite, glucose, and fat metabolism. Semaglutide, Tirzepatide, and Retatrutide mimic GLP-1 and related gut hormones to slow digestion and suppress appetite, while Cagrilintide works through a related amylin-receptor pathway; AOD-9604 and MOTS-c instead act through non-incretin mechanisms — a lipolysis fragment of growth hormone and mitochondrial AMPK signaling, respectively. Of the 16 compounds profiled here, this category carries the deepest human evidence of any research-peptide area, because several of these compounds completed full commercial drug development.