Does BPC-157 need to be refrigerated?

FDA's briefing document for its July 2026 Pharmacy Compounding Advisory Committee reports that freeze-dried (lyophilized) BPC-157 is stable at room temperature for 3 weeks, but recommends storage desiccated below -18°C, because moisture greatly decreases the long-term stability of freeze-dried peptides. Once reconstituted, it reports BPC-157 in solution stable for 2–3 weeks at 4°C and for 3–4 months at -20°C1.

• One clinic stores the vial upright in the refrigerator at 35–46°F and gives reconstituted BPC-157 2–4 weeks refrigerated2.
• Another refrigerates it after reconstitution, says the unreconstituted powder can be kept at room temperature, and ships it overnight refrigerated3.
• A clinician-reviewed guide stores the powder in the refrigerator or freezer as directed and uses a mixed vial within the recommended window, often 7–14 days in the fridge4.

None of these figures comes from a label for an approved product, because there is none: BPC-157 is not FDA-approved. FDA's figures are reported values in a briefing document, and the clinic windows differ from one another, from one to four weeks. No published study in people has tested how long a reconstituted vial keeps its potency.

How BPC-157 is reconstituted and administered is set out in How is BPC-157 taken?.

The arithmetic for each vial size and water volume is in the BPC-157 reconstitution calculator.